TRETINOIN NANOGEL 0.025% VERSUS CONVENTIONAL GEL 0.025% IN PATIENTS WITH ACNE VULGARIS: A RANDOMIZED, ACTIVE CONTROLLED, MULTICENTRE, PARALLEL GROUP, PHASE IV CLINICAL TRIAL

Background: Conventional topical tretinoin formulation is often associated with local adverse events.Nanogel formulation of tretinoin has good physical stability and enables good penetration of tretinoin into the pilo-sebaceous glands.Aim: The present study was conducted to assess the efficacy and safety of a nanogel formulation of tretinoin as com

It has been established that low concentrations of hydrogen peroxide (H(2)O(2)) are produced in wounds and is required for optimal healing.Yet at the same time, there is evidence that excessive oxidative damage is correlated with poor-healing wounds.In this paper, we seek to determine whether topical application of H(2)O(2) can modulate wound heali

With a wide spectrum of data, case studies, monitoring, and experimental and numerical simulation techniques, the multidisciplinary approach of material, environmental, and computer science applied to the conservation of cultural heritage offers several opportunities for the heritage science and conservation community to map and monitor the state o

The purpose of the study is to analyse the regulatory potential of international law taking into account its main focus for the regulation of new relations associated with digitalisation processes.The research methodology consisted of formal-legal, formal-logical, interpretation of law as well as general-scientific methods.The research resulted in

This paper presents an analysis of the case of multicriteria choice of promotion form for a product group, in one large retail chain.The following forms of promotion were available: commercial propaganda, personal selling, sales promotion, publicity, public relations and direct marketing.The selection was made on the basis of five criteria: the eff